Is Novavax a Viable and Possibly Safer Alternative to the Pfizer and Moderna Jabs, as in, a Real Vaccine?

By Jerry PDX
Monday, November 1, 2021 at 1:32:00 P.M. EDT

Is Novovax a viable and possibly safer alternative to Pfizer and Moderna vaccines?

https://www.nebraskamed.com/COVID/moths-and-tree-bark-how-the-novavax-vaccine-works

Novavax doesn’t use mRna to manipulate your cells into creating spike proteins, but supplies the proteins in the vaccine, and is derived from moth cells and tree bark. Human testing is just beginning but like the other Covid vaccines, long-term effects are unknown.

From the article:

The Novavax method uses moth cells to make spike proteins:

Researchers select the desired genes that create certain SARS-CoV-2 antigens (spike protein).

Researchers put the genes into a baculovirus, an insect virus.

The baculovirus infects moth cells and replicates inside them.

These moth cells create lots of spike proteins.

Researchers extract and purify the spike proteins.

“The Novavax vaccine has no genetic material, only proteins,” says Dr. Florescu. “The vaccine technology is more traditional, and it’s very similar to a protein-based influenza vaccine.”

Influenza vaccines have also used this moth cell factory method.

What does the adjuvant (soapbark tree extract) do?

Adjuvants increase the immune response to a vaccine. In this vaccine, soapbark tree extract adjuvant makes achieving immunity possible with a smaller dose of the spike protein.

Matrix-M is the adjuvant used by Novavax. It is based on a saponin extracted from the soapbark tree (Quillaja saponaria). The soapbark extract encourages immune cells to activate, generating a more potent immune response.

Saponins are found naturally in various plant species like beans and green peas. They're used in agriculture, animal feeds, veterinary vaccines and human food. Saponins can boost immune responses to proteins. Using the Matrix-M adjuvant, a smaller dose of spike protein achieves the desired immune response.



By Eahilf

Monday, November 1, 2021 at 3:24:00 P.M. EDT

“Novavax doesn’t use mRna to manipulate your cells into creating spike proteins.”

The recombinant vaccine for Hepatitis B (link) was approved more than 35 years ago, and is made by inserting the genetic material from the Hepatitis B virus (HBV) that encodes for a surface antigen (“spike” protein) into yeast cells, inducing them to produce the HPV protein, which is then made into a vaccine.

So back when the mRNA vaccine for COVID was introduced, I asked why it was not produced in the same way, i.e., by using recombinant DNA technology to get e.g. yeast cells to produce a spike protein/antigen of SARS-CoV-2?

There are, no doubt, patents associated with the recombinant technology and method of producing the vaccine, but normally those expire after 20 years – ?